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Maternal generalized anxiety disorder during pregnancy and fetal brain development: a comparative study on cord blood brain-derived neurotrophic factor levels.
Contributors
Uguz F, Sonmez EO, Sahingoz M, Gokmen Z, Basaran M, Gezginc K, Sonmez G, Kaya N, Erdem SS, Cicekler H, Tasyurek E.
The study aimed to investigate whether maternal GAD during pregnancy affects fetal circulating brain-derived neurotrophic factor (BDNF), which plays important roles in neuronal development, by comparing cord blood BDNF levels in newborn infants of women with and without GAD.
The study results imply that prolonged maternal GAD during pregnancy may negatively influence neurodevelopment of the fetusthrough lower levels of circulating BDNF.
Copyright © 2013 Elsevier Inc. All rights reserved.
PMID:24119941
[PubMed – in process]
LINK – J Psychosom Res. 2013 Oct;75(4):346-50. doi: 10.1016/j.jpsychores.2013.04.010. Epub 2013 May 22